In this study, the properties of glass/polyphenylene sulfide commingled hybrid fibers were first investigated, including physical, thermal, and SEM images, and then the effect of fiber arrangement on the mechanical properties of glass-fiber reinforced thermoplastic composites in polyphenylene sulfide was also investigated. Composite sheets were fabricated using glass-comingel/PPS hybrid yarns through a hot pressing process in two different configurations: (1) reinforced with continuous, unidirectional fibers and (2) reinforced with short fibers and randomly arranged. The main objective was to directly compare the interlaminar shear strength (ILSS) and tensile properties of these two structures in order to understand the role of fiber orientation in the final product performance. The results of mechanical tests showed strong anisotropy in unidirectional samples; such that the tensile strength in the longitudinal direction (289 MPa) was much higher than that in the transverse direction (5 MPa) and chopped fiber samples (61 MPa). Similarly, the ILSS value of the unidirectional sample (18.7 MPa) was significantly higher than that of the random fiber samples (7 MPa). The main novelty of this study is its focus on glass/PPS fibers, the use of hybrid commingled yarn to improve impregnation and integration of the fibers and matrix, and the direct comparison of two reinforcement configurations, namely continuous unidirectional fibers and short fibers with random distribution.